Description:
Handbook of
Hematologic Malignancies provides a unique, practical, and concise
guide focused on the must-know points of diagnosis, prognosis, therapeutic
management, and cutting edge clinical trial opportunities for each hematologic
malignancy. With an ever-increasing growth of evidence and a significant
expansion of available treatment options for patients with hematologic disease,
remaining current and up-to-date can be extremely challenging for practicing
clinicians. This comprehensive subspecialty handbook is designed and organized
for the busy hematologist, hematologic oncologist, hematopathologist, and
trainee in mind.
Every chapter is
richly illustrated with color figures and flow diagrams, and contains helpful
tables on differential diagnosis, prognostic scoring systems and therapeutic
options. A concise case-based review for testing pathologic diagnosis and
clinical knowledge for each chapter is included for digital download online and
in the e-book. Written by experienced clinicians at the world-renowned Moffitt
Cancer Center in Tampa, Florida, as well as contributions from leading
academicians throughout the country, this handbook is an essential resource for
anyone diagnosing, treating, or managing patients with hematologic malignancy.
KEY FEATURES:
- Contains clear prognostic and diagnostic tools (e.g.,
tables/flow diagrams/pathology images) with emphasis on key differential
diagnoses and diagnostic dilemmas
- Easy to use treatment recommendations with bullet
point format and key references
- Discusses the future of patient management based on
practice changing clinical trials
- Includes
access to digitally downloadable case-based clinical scenarios and questions
with high resolution pathology images linked to each individual chapter
Contents:
Contributors
Expert Reviewers
Foreword John M. Bennett, MD
Preface
Abbreviations
INTRODUCTION AND OVERVIEW
Chapter 1. Hematopathology
Diagnostic Techniques and Assays (Johnny Nguyen and Ling Zhang)
MYELOPROLIFERATIVE NEOPLASMS
Chapter 2. Polycythemia Vera
(Liliana Bustamante and Kenneth Zuckerman)
Chapter 3. Essential
Thrombocythemia (Susmitha Apuri and Kenneth Zuckerman)
Chapter 4. Primary Myelofibrosis (Andrew Kuykendall and Kenneth
Zuckerman)
Chapter 5. Chronic Myelogenous Leukemia (Chetasi Talati and
Javier Pinilla-Ibarz)
Chapter 6. Chronic Neutrophilic Leukemia (Saman Nematollahi,
Shweta Jain, and Utkarsh Acharya)
Chapter 7. Systemic Mastocytosis (Andrew Kuykendall and Kenneth
Zuckerman)
Chapter 8. PDGFRA/PDGFRB/FGFR1 Myeloid Neoplasms (Joseph
Clara and Eric Padron)
Myelodysplastic and Bone
Marow Failure Syndromes
Chapter 9. Myelodysplastic Syndromes (Joanna Grabska, David A. Sallman, and Rami
Komrokji)
Chapter 10. Aplastic Anemia (Michael Shafique and Rami Komrokji)
Chapter 11. Paroxysmal Nocturnal Hemoglobinuria (Hilda Ding and
Michael Jaglal)
MYELODYSPLASTIC/Myeloproliferative
Neoplasms
Chapter 12. Myelodysplastic/Myeloproliferative Overlap Syndromes
(Jennifer Eatrides and Eric Padron)
Chapter 13. Chronic Myelomonocytic Leukemia (Alexandra Gomez and
Justin M. Watts)
ACUTE MYELOID LEUKEMIA AND RELATED SYNDROMES
Chapter 14. Acute Myeloid
Leukemia (Varun Dhulipala and Kendra Sweet)
Chapter 15. Secondary AML and AML With Myelodysplasia-Related
Changes (Seongseok Yun and Jeffrey Lancet)
Chapter 16. Acute Promyelocytic Leukemia (Leidy L. Isenalumhe and
Jeffrey Lancet)
Chapter 17. Blastic Plasmacytoid Dendritic Cell Neoplasm (Justin
Taylor, Ateefa Chaudhury, and Andrew A. Lane)
ACUTE LYMPHOID LEUKEMIA
Chapter 18. B-Lymphoblastic
Leukemia (Aneesha Hossain and Khaled el-Shami)
Chapter 19. BCR-ABL1+ B-Lymphoblastic Leukemia (Aneesha
Hossain and Khaled el-Shami)
Chapter 20. T-Lymphoblastic
Lymphoma/Leukemia (Keri Maher and Ravitharan Krishnadasan)
ACUTE LEUKEMIA OF AMbIGUOUS
LINEAGE
Chapter 21. Acute Leukemia of
Ambiguous Lineage (Keri Maher and Ravitharan Krishnadasan)
MATURE T- AND NK-CELL LEUKEMIA
Chapter 22. T-Cell Prolymphocytic
Leukemia (Abhijeet Kumar, Srinath Sundararajan, and Ravitharan Krishnadasan)
Chapter 23. T-Cell Large Granular Lymphocytic Leukemia (Magali
Van den Bergh and Lubomir Sokol)
Chapter 24. Aggressive Natural Killer Cell Leukemia (Mintallah
Haider and Lubomir Sokol)
PLASMA CELL DISORDERS
Chapter 25. Monoclonal Gammopathy
of Unknown Significance, Smoldering Myeloma, and Plasmacytomas (Srinath
Sundararajan, Abhijeet Kumar, Amit Agarwal, and Neha Korde)
Chapter 26. Multiple Myeloma (Patrick Griffin and Rachid Baz)
Chapter 27. Waldenström’s Macroglobulinemia (Joanna Grabska and
Rachid Baz)
Chapter 28. Immunoglobulin Light Chain Amyloidosis (Taxiarchis
Kourelis and Morie A. Gertz)
Hodgkin Lymphoma
Chapter 29. Hodgkin Lymphoma
(Anju Nair and Micah Burch)
NON-HODGKIN LYMPHOMA
Chapter 30. Non-Hodgkin Lymphoma
Classification and Diagnostic Evaluation (Johnny Nguyen and Ling Zhang)
MATURE B-CELL LYMPHOMA
VERY AGGRESSIVE
Chapter 31. Burkitt Lymphoma
(Anju Nair and Micah Burch)
AGGRESSIVE
Chapter 32. Diffuse Large B-Cell
Lymphoma (Jose Sandoval-Sus and Julio Chavez)
Chapter 33. Double Hit Lymphoma
(Nikhil Mukhi and Julio Chavez)
Chapter 34. Mantle Cell Lymphoma (Samantha Shams and Bijal Shah)
Chapter 35. Primary Mediastinal Large B-Cell Lymphoma (Andreas
Saltos and Julio Chavez)
Chapter 36. Primary Central
Nervous System Lymphoma (Liliana Bustamante and Peter Forsyth)
Chapter 37. HIV-Related Lymphomas
(Danny Nguyen, Nishan Tchekmedyian, and Jeremy Abramson)
INDOLENT
Chapter 38. Follicular Lymphoma (Asha Balakrishnan and Celeste Bello)
Chapter 39. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
(Ateefa Chaudhury and
Javier Pinilla-Ibarz)
Chapter 40. Hairy Cell Leukemia (Justin Taylor and Omar Abdel-Wahab)
Chapter 41. Marginal Zone Lymphoma (Nishan Tchekmedyian, Danny
Nguyen, and Celeste Bello)
Chapter 42. Mucosa-Associated Lymphoid Tissue Lymphoma (Ridhi
Gupta, Matthew Mastrodomenico,
Nishan Tchekmedyian, and Saurabh Chhabra)
MATURE T/NK-CELL LYMPHOMA
Chapter 43. Adult T-Cell
Leukemia/Lymphoma (Nikhil Mukhi and Lubomir Sokol)
Chapter 44. Anaplastic Large Cell Lymphoma, ALK Positive (Thomas
Enzler and Changchun Deng)
Chapter 45. Extranodal Natural Killer/T-Cell Lymphoma (Joseph Clara
and Lubomir Sokol)
Chapter 46. Mycosis Fungoides (Achuta Kumar Guddati and Lubomir
Sokol)
Chapter 47. Hepatosplenic T-Cell Lymphoma (Narendranath Epperla,
Apoorva Jayarangaiah, and Timothy S. Fenske)
HISTIOCYTIC/DENDRITIC CELL NEOPLASMS
Chapter 48. Histiocytic Sarcoma
and Langerhans Cell Histiocytosis (Narendranath Epperla and Ehab Atallah)
Chapter 49. Hemophagocytic Lymphohistiocytosis (Hilda Ding and
Lubomir Sokol)
BONE MARROW TRANSPLANTATION
Chapter 50. Autologous Bone Marrow Transplantation (Hemant S.
Murthy and Mohamed A. Kharfan-Dabaja)
Chapter 51. Allogeneic Bone Marrow Transplantation (Hemant S.
Murthy, Taiga Nishihori, and
Mohamed A. Kharfan-Dabaja)
EMERGENCIES IN HEMATOLOGY
Chapter 52. Tumor Lysis Syndrome
(Mintallah Haider, Ateefa Chaudhury, and Michael Jaglal)
Chapter 53. Thrombotic Microangiopathy (Ruchika Goel, Aaron
Tobian, and Ljiljana V. Vasovic)
Chapter 54. Therapeutic Apheresis Indications (Amanda E. Lo,
Ruchika Goel, and Ljiljana V. Vasovic)
Appendix: Pathology Supplement
Index
About the Editors:
David A. Sallman, MD
Department of Malignant Hematology
H. Lee Moffitt Cancer Center & Research Institute
University of South Florida
Tampa, Florida
Ateefa Chaudhury, MD
Department of Malignant Hematology
H. Lee Moffitt Cancer Center & Research Institute
University of South Florida
Tampa, Florida
Johnny Nguyen, MD
Department of Hematopathology
H. Lee Moffitt Cancer Center & Research Institute
University of South Florida
Tampa, Florida
Ling Zhang, MD
Department of Hematopathology
H. Lee Moffitt Cancer Center & Research Institute
University of South Florida
Tampa, Florida
Alan F. List, MD
Department of Malignant Hematology
H. Lee Moffitt Cancer Center & Research Institute
University of South Florida
Tampa, Florida
Target Audience:
Hematologist,
hematologic oncologist, hematopathologist, and trainees.